Home > Clinical question: How effective and safe are electronic cigarettes (ECs) for smoking cessation?

Tort, Sera and Fowler, Cathryn (2024) Clinical question: How effective and safe are electronic cigarettes (ECs) for smoking cessation? Cochrane Clinical Answers, https://doi.org/10.1002/cca.4435.

External website: https://www.cochranelibrary.com/cca/doi/10.1002/cc...


Based on high‐ to moderate‐certainty evidence, more people quit smoking using nicotine ECs compared with nicotine replacement therapy (NRT) or nicotine‐free ECs, with no concomitant increase in medium‐term adverse events; however, the proportion of people quitting was very low (on average, 156 and 58 per 1000 people with nicotine ECs vs 99 and 40 per 1000 people with NRT and nicotine‐free ECs, respectively). Evidence comparing nicotine‐containing ECs versus behavioral support is very uncertain.

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