As the United States grapples with the persistent challenges of chronic pain and substance use disorder (SUD), the rise in telehealth has opened new horizons for health care delivery. This paper delineates a comprehensive action agenda for the development of hybrid care models, combining the strengths of telehealth and traditional in-person care to address the individual and intersecting needs of chronic pain and SUD management. At the core of this agenda are four cross-cutting areas of opportunity:

• Centering the Lived Experiences of Patients and Caregivers to enrich care design and execution
• Enhancing Workforce Support and Infrastructure Capacity to support the implementation of hybrid care models
• Focusing on Safety and Quality of Care to maintain high standards in telehealth and in-person services
• Aligning Regulations and Payment Policies with Evidence-Based Care to foster a more supportive and less burdensome regulatory environment