Roehrs, Timothy and Sibai, Mohammad and Roth, Thomas (2021) Sleep and alertness disturbance and substance use disorders: a bi-directional relation. Pharmacology, Biochemistry, and Behavior, 203, 173153. doi: 10.1016/j.pbb.2021.173153.
External website: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC79969...
The majority of the literature describing the relation of sleep/alertness disturbance and substance use disorders (SUD) has focused on the disruptive effects of substances with abuse liability on sleep and alertness. Rarely have studies or literature reviews assessed or discussed how sleep/alertness disturbance affects substance use. This paper focuses on the sleep/alertness disturbance side of the relation. We argue that the relation is bi-directional and review evidence showing that sleep/alertness disturbance affects all phases of the addiction cycle, including the initiation, maintenance and relapse of SUD. We review a variety of substances across all phases of the addiction cycle and conclude sleep/alertness disturbance is a critical factor in both understanding and treating SUD.
A Substance use and dependence > Personal history of substance use (pathway) > Relapse / Recurrence
F Concepts in psychology > State of consciousness (sleep)
J Health care, prevention, harm reduction and treatment > Risk and protective factors > Risk factors
VA Geographic area > United States
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