Dixon, David I and Millea, Molly F and Wilcock, Alexander TM and Costello, Andrew and Ellison, Jamie R and Lord, Sacha and O'Brian, Kim A and Mewis, Ryan E and Sutcliffe, Oliver B (2023) Synthesis, characterisation and quantification of the new psychoactive substance 1-(1,3-benzodioxol-5-yl)-2-(propylamino)butan-1-one (bk-PBDB, putylone). Forensic Chemistry, 100523. doi.org/10.1016/j.forc.2023.100523.
External website: https://www.sciencedirect.com/science/article/pii/...
Synthetic cathinones are a continually evolving family of illicit drugs, with novel analogues frequently being detected. This paper reports the detection of 1-(1,3-benzodioxol-5-yl)-2-(propylamino)butan-1-one, bk-PBDB (putylone), within solid dosage forms (tablets) seized by law enforcement for the first time in the United Kingdom.
Highlights:
• Novel synthetic cathinone bk-PBDB was detected in a seized solid dosage form.
• Synthesis of bk-PBDB reference standard for comparison.
• Full NMR, ATR-FTIR and GC-EI-MS characterisation of bk-PBDB is reported.
• Development and validation of GC-EI-MS method of quantification.
• Seized samples were determined by GC-EI-MS to contain a combination of bk-PBDB (130.6–135.5 mg/tablet) and caffeine (40.2–43.4 mg/tablet).
B Substances > New (novel) psychoactive substances > Synthetic cathinones
E Concepts in biomedical areas > Pharmacology and toxicology
MM-MO Crime and law > Substance related offence > Drug offence > Illegal drug possession (seizures)
VA Geographic area > Europe > United Kingdom
Repository Staff Only: item control page