Importance: Cannabis use is increasingly viewed by adolescents as not harmful. Youths with cannabis use disorder (CUD) are recognized by clinicians as being at risk for adverse outcomes, yet little is known about the associations between subclinical cannabis use (ie, nondisordered cannabis use [NDCU]) and adverse psychosocial events.

Question: Is nondisordered cannabis use (NDCU) among US adolescents associated with adverse psychosocial events?

Findings: In this cross-sectional study of 68 263 adolescents, NDCU was approximately 4 times more common than cannabis use disorder (CUD). NDCU and CUD were both significantly associated with adverse psychosocial events in a stepwise gradient manner.

Meaning: These findings suggest that adolescents with NDCU or CUD had increased odds of adverse psychosocial events.