The aim of the orientation pack is to standardise the training and education of clinical research nurses and midwives in Ireland. It will orientate you to the clinical research environment and the role and responsibilities of the clinical research nurse. Learning about clinical research, the people involved, systems and procedures is likely to be an incremental process and much learning will occur informally in the workplace. This pack will provide a structure for self-directed and/or supported orientation, and an introduction to clinical research processes and governance. It will provide you with information about the relevant legislation and regulations underpinning clinical research and the role and responsibilities of a clinical research nurse.