Johnson, Natalie L and Patten, Theresa and Ma, Minghong and De Biasi, Mariella and Wesson, Daniel W (2022) Chemosensory contributions of e-cigarette additives on nicotine use. Frontiers in Neuroscience, 16, 893587. doi: 10.3389/fnins.2022.893587.
External website: https://www.frontiersin.org/articles/10.3389/fnins...
While rates of smoking combustible cigarettes in the United States have trended down in recent years, use of electronic cigarettes (e-cigarettes) has dramatically increased, especially among adolescents. The vast majority of e-cigarette users consume "flavored" products that contain a variety of chemosensory-rich additives, and recent literature suggests that these additives have led to the current "teen vaping epidemic." This review, covering research from both human and rodent models, provides a comprehensive overview of the sensory implications of e-cigarette additives and what is currently known about their impact on nicotine use. In doing so, we specifically address the oronasal sensory contributions of e-cigarette additives. Finally, we summarize the existing gaps in the field and highlight future directions needed to better understand the powerful influence of these additives on nicotine use.
[Note, this article is one of four articles examining 'Pharmacological and behavioral effects of added flavorants on tobacco addiction'. Also included is the mini-review: Flavor science in the context of research on electronic cigarettes]
E Concepts in biomedical areas > Nervous system physiology (brain, neural)
J Health care, prevention, harm reduction and treatment > Risk and protective factors > Risk factors
VA Geographic area > International
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