Home > Effects of interventions to combat tobacco addiction: Cochrane update of 2019 and 2020 reviews.

Livingstone-Banks, Jonathan and Lindson, Nicola and Hartmann-Boyce, Jamie and Aveyard, Paul (2022) Effects of interventions to combat tobacco addiction: Cochrane update of 2019 and 2020 reviews. Addiction, 117, (6), pp. 1526-1542. doi: 10.1111/add.15769.

External website: https://onlinelibrary.wiley.com/doi/10.1111/add.15...

Aims: To summarize evidence on tobacco addiction interventions published by the Cochrane Tobacco Addiction Group (CTAG) from 2019 to 2020.

Methods: Narrative summary of all new and updated Cochrane Reviews published by CTAG in 2019 and 2020, outlining key results and promising avenues for future research.

Results: CTAG published six new reviews and updated 15 reviews. There is high-certainty evidence that combining fast-acting nicotine replacement therapy (NRT) with transdermal patches helped more people to quit than single-form NRT and moderate-certainty evidence that using NRT before quitting can increase quit rates more than using NRT from quit day onwards. Reducing smoking in order to quit completely results in similar quit rates to abrupt quitting. Electronic cigarettes may help more people quit than NRT nicotine-free electronic cigarettes and behavioural/no support. Varenicline may help prevent relapse in abstainers, but behavioural support did not prevent relapse. Financial incentives increased quit rates in the general population and during pregnancy. This overview also provides detail on a wider range of interventions.

Conclusions: There is high certainty that using nicotine replacement therapy from quit day increases smoking abstinence and no further research is required. Evidence is less certain that nicotine replacement increases abstinence when used in higher doses tailored to particular groups of smokers or use prior to quit day, and further research would be helpful. There is moderate-certainty evidence to support the use of e-cigarettes as cessation aids, but research on their role in preventing relapse would be particularly helpful.

Item Type
Publication Type
International, Open Access, Review, Article
Drug Type
Tobacco / Nicotine
Intervention Type
Drug therapy, Treatment method
June 2022
Identification #
doi: 10.1111/add.15769
Page Range
pp. 1526-1542

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