Home > Effectiveness of e-cigarettes as aids for smoking cessation: evidence from the PATH study cohort, 2017–2019.

Chen, Ruifeng and Pierce, John P and Leas, Eric C and Benmarhnia, Tarik and Strong, David R and White, Martha M and Stone, Matthew D and Trinidad, Dennis R and McMenamin, Sara B and Messer, Karen (2022) Effectiveness of e-cigarettes as aids for smoking cessation: evidence from the PATH study cohort, 2017–2019. Tobacco Control, Early online, doi: 10.1136/tobaccocontrol-2021-056901.

External website: https://tobaccocontrol.bmj.com/content/early/2022/...

Objective: To assess the effectiveness of e-cigarettes in smoking cessation in the USA from 2017 to 2019, given the 2017 increase in high nicotine e-cigarette sales.

Methods: In 2017, the PATH Cohort Study included data on 3578 previous year smokers with a recent quit attempt and 1323 recent former smokers. Respondents reported e-cigarettes or other products used to quit cigarettes and many covariates associated with e-cigarette use. Study outcomes were 12+ months of cigarette abstinence and tobacco abstinence in 2019. We report weighted unadjusted estimates and use propensity score matched analyses with 1500 bootstrap samples to estimate adjusted risk differences (aRD).

Results: In 2017, 12.6% of recent quit attempters used e-cigarettes to help with their quit attempt, a decline from previous years. Cigarette abstinence for e-cigarette users was lower than for no product use, and the aRD for e-cigarettes versus pharmaceutical aids was −7.3% and for e-cigarettes versus any other method was −7.7%. Only 2.2% of recent former smokers switched to a high nicotine e-cigarette. Subjects who switched to e-cigarettes appeared to have a higher relapse rate than those who did not switch to e-cigarettes or other tobacco, although the difference was not statistically significant.

Conclusions: Sales increases in high nicotine e-cigarettes in 2017 did not translate to more smokers using these e-cigarettes to quit smoking. On average, using e-cigarettes for cessation in 2017 did not improve successful quitting or prevent relapse.

Item Type
Publication Type
International, Open Access, Article
Drug Type
Tobacco / Nicotine
Intervention Type
Treatment method
February 2022
Identification #
doi: 10.1136/tobaccocontrol-2021-056901
BMJ Publishing
Early online

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