Home > Birth outcomes of neonates exposed to marijuana in utero: a systematic review and meta-analysis.

Marchand, Greg and Masoud, Ahmed Taher and Govindan, Malini and Ware, Kelly and King, Alexa and Ruther, Stacy and Brazil, Giovanna and Ulibarri, Hollie and Parise, Julia and Arroyo, Amanda and Coriell, Catherine and Goetz, Sydnee and Karrys, Amitis and Sainz, Katelyn (2022) Birth outcomes of neonates exposed to marijuana in utero: a systematic review and meta-analysis. JAMA Network Open, 5, (1), e2145653. doi: 10.1001/jamanetworkopen.2021.45653.

External website: https://jamanetwork.com/journals/jamanetworkopen/f...

Question: Are adverse neonatal outcomes associated with exposure to marijuana among mothers during pregnancy?

Findings: In this meta-analysis of 16 studies including 59 138 patients, maternal marijuana exposure during pregnancy was associated with increased risk of preterm deliveries and neonatal intensive care unit admission and decreased mean birth weight, 1-minute Apgar score, and head circumference of babies. There were no differences in mean 5-minute Apgar score or total infant length.

Meaning: This study found that women using marijuana during pregnancy may be at increased risk of some adverse neonatal outcomes.


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