Tadrous, Mina and Shakeri, Ahmad and Chu, Cherry and Watt, Jennifer and Mamdani, Muhammad M and Juurlink, David N and Gomes, Tara (2021) Assessment of stimulant use and cardiovascular event risks among older adults. JAMA Network Open, 4, (10), e2130795. doi: 10.1001/jamanetworkopen.2021.30795.
External website: https://jamanetwork.com/journals/jamanetworkopen/f...
Question: Is prescription stimulant use associated with an increased risk of cardiovascular (CV) events among adults aged 66 years and older?
Findings: In this cohort study of 6457 older adults who initiated stimulant use and 24 853 matched older adults who did not initiate such use, stimulant use was associated with a 40% increase in CV events within 30 days of initiation. Risk attenuated over time, with no association with increased risk at 180 days or 365 days after initiation.
Meaning: These findings suggest that safety considerations should be included when stimulants are prescribed to older adults.
B Substances > CNS stimulants
E Concepts in biomedical areas > Medical substance > Prescription drug (medicine / medication)
G Health and disease > State of health > Physical health
G Health and disease > Cardiovascular / heart disease
T Demographic characteristics > Elderly / Older person
VA Geographic area > Canada
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