Home > The Lancet Psychiatry: Single dose of psychoactive component in cannabis could induce psychotic, depressive, and anxiety symptoms in healthy people.

Lancet Press Office. (2020) The Lancet Psychiatry: Single dose of psychoactive component in cannabis could induce psychotic, depressive, and anxiety symptoms in healthy people. EurekAlert

URL: https://www.eurekalert.org/pub_releases/2020-03/tl...

• In addition, the review found no consistent evidence that cannabidiol (CBD) moderates the effects of tetrahydrocannabinol (THC - the psychoactive component of cannabis) in healthy volunteers
• Single dose of THC, roughly equivalent to smoking one joint, may induce a variety of psychiatric symptoms associated with schizophrenia and other psychiatric disorders. These effects are larger with intravenous administration than with inhaled administration, while tobacco smokers have fewer symptoms - though the authors stress that further work is needed to test this, and this finding should not be taken as a recommendation to use tobacco to counter the effects of THC.
• These findings highlight the risks of cannabis use, which are highly relevant as medical, societal, and political interest in cannabinoids continues to grow.

Item Type:Evidence resource
Publication Type:Review
Drug Type:Cannabis
Intervention Type:AOD disorder, AOD disorder harm reduction
Date:17 March 2020
Corporate Creators:Lancet Press Office
EndNote:View
Subjects:A Substance use, abuse, and dependence > Effects and consequences
B Substances > Cannabis / Marijuana
F Concepts in psychology > Emotion (anxiety, emotional pain)
G Health and disease > State of health > Mental health
G Health and disease > Substance related disorder > Substance related mental disorder

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