Home > Clinical question: Can adding baclofen to psychosocial treatment improve outcomes for people with alcohol use disorder?

Kavirajan, Harish [The Cochrane Library] . (2019) Clinical question: Can adding baclofen to psychosocial treatment improve outcomes for people with alcohol use disorder? London: Wiley. Cochrane Clinical Answers https://doi.org/10.1002/cca.2457

URL: https://www.cochranelibrary.com/cca/doi/10.1002/cc...


Not only have clinical trials failed to demonstrate benefits over placebo from adding baclofen to psychosocial treatment for alcohol use disorder, they have also suggested that baclofen increases rates of various adverse events such as dizziness, somnolence, paresthesias, and muscle spasms/rigidity. Despite elevated rates of such adverse events, rates of withdrawal due to adverse events or for any cause were similar in both groups.

Item Type:Evidence resource
Drug Type:Alcohol
Intervention Type:AOD disorder, AOD disorder drug therapy, AOD disorder treatment method, Psychosocial treatment method
Source:The Cochrane Library
Date:July 2019
Publisher:Wiley
Place of Publication:London
EndNote:View
Subjects:B Substances > Alcohol
G Health and disease > Substance use disorder > Alcohol use > Alcohol dependence
HJ Treatment method > Substance disorder treatment method > Substance disorder drug therapy
HJ Treatment method > Psychosocial treatment method
HJ Treatment method > Treatment outcome
J Health care, prevention and rehabilitation > Patient care management

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