Strand, Maren Cecilie and Vindenes, Vigdis and Gjerde, Hallvard and Mørland, Jørg Gustav and Ramaekers, Johannes G (2019) A clinical trial on the acute effects of methadone and buprenorphine on actual driving and cognitive function of healthy volunteers. British Journal of Clinical Pharmacology, 85, (2), https://doi.org/10.1111/bcp.13818.
External website: https://bpspubs.onlinelibrary.wiley.com/doi/abs/10...
The present study assessed the acute effects of methadone and buprenorphine on actual on‐road driving performance and neurocognitive function.
Analgesic doses of buprenorphine produced mild impairing effects on driving and related cognitive skills, while methadone impaired cognitive task performance but not driving performance. Large individual variations were observed for both drugs. Patients should be informed about the possibility of driving impairment when initiating opioid treatment.
A Substance use and dependence > Substance related societal (social) problems > Drug use and driving
B Substances > Opioids (opiates) > Opioid product > Buprenorphine / Suboxone
B Substances > Opioids (opiates) > Opioid product > Methadone
E Concepts in biomedical areas > Medical substance > Prescription drug (medicine / medication)
J Health care, prevention, harm reduction and treatment > Patient / client care management
VA Geographic area > Europe > United Kingdom
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