Home > Clinical question: How does varenicline compare with bupropion or nicotine‐replacement therapy for smoking cessation?

Bunt, Christopher (2017) Clinical question: How does varenicline compare with bupropion or nicotine‐replacement therapy for smoking cessation? Cochrane Clinical Answers,

External website: https://www.cochranelibrary.com/cca/doi/10.1002/cc...

Varenicline improved abstinence compared with bupropion or nicotine replacement therapy (NRT), but was more likely than placebo to lead to nausea, insomnia, abnormal dreams, headaches and serious adverse events. The lack of comparative adverse effects assessment of varenicline with bupropion or NRT means that firm conclusions of the overall comparative effects of these interventions cannot be drawn.


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