Cayley, William (2015) Clinical question: Can acamprosate (with or without naltrexone) support continued abstinence after detoxification in alcohol‐dependent people? Cochrane Clinical Answers .
External website: https://www.cochranelibrary.com/cca/doi/10.1002/cc...
Randomized controlled trials suggest that acamprosate may be more effective than placebo for reducing return to drinking but may increase diarrhea. Acamprosate and naltrexone seem to be equally effective but naltrexone seems to cause a wider range of adverse effects. Adding naltrexone to acamprosate did not confer additional benefit and increased adverse effects.....
B Substances > Alcohol
B Substances > Opioids (opiates) > Opioid product > Naltrexone
G Health and disease > Substance use disorder > Alcohol use disorder > Alcohol dependence
HJ Treatment method > Substance disorder treatment method > Substance disorder drug therapy
J Health care, prevention, harm reduction and rehabilitation > Patient / client care management
J Health care, prevention, harm reduction and rehabilitation > Health care delivery
J Health care, prevention, harm reduction and rehabilitation > Health care administration > Health care quality control
N Communication, information and education > Recommendations > Practice / clinical guidelines
VA Geographic area > International
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