Home > No clear role for medications in less dependent drinkers.

[Drug and Alcohol Findings] (2018) No clear role for medications in less dependent drinkers. London: Drug and Alcohol Findings. Drug and Alcohol Findings Bulletin (18 January 2018) 4 p.

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URL: http://findings.org.uk/PHP/dl.php?file=Palpacuer_C...

Key points from summary and commentary:
In 2013 nalmefene was authorised for moderating drinking among patients not in need of detoxification, extending pharmacotherapy to less dependent drinkers.

The featured review examined whether other medications (naltrexone, acamprosate, baclofen, and topiramate) have been found to do this just as well.

There was no high quality evidence for any of the medications, though nalmefene, topiramate and baclofen moderated consumption, and topiramate also consistently reduced other measures of drinking. No evidence was found that nalmefene was superior to the other medications, or that any improved health.

Safety concerns mean topiramate and baclofen are not recommended for alcohol dependence in the UK.


Item Type:Evidence resource
Drug Type:Alcohol
Intervention Type:AOD disorder, AOD disorder drug therapy, AOD disorder treatment method
Source:Drug and Alcohol Findings
Date:January 2018
Pages:4 p.
Publisher:Drug and Alcohol Findings
Place of Publication:London
Number:18 January 2018
EndNote:View
Subjects:A Substance use, abuse, and dependence > Prevalence > Substance use behaviour > Alcohol consumption
B Substances > Alcohol
B Substances > Opioids (opiates) > Opioid product > Naltrexone
E Concepts in biomedical areas > Substance by legal status > Prescription drug (medicine / medication)
G Health and disease > Substance use disorder > Alcohol use > Alcohol dependence
HJ Treatment method > Substance disorder treatment method > Substance disorder drug therapy
VA Geographic area > Europe > United Kingdom

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