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Home > Naltrexone and acamprosate best suited to different alcohol treatment goals.

Drug and Alcohol Findings. (2016) Naltrexone and acamprosate best suited to different alcohol treatment goals. Drug and Alcohol Findings Research Analysis , (13 December 2016) .

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Naltrexone and acamprosate both modestly curtail drinking among alcohol-dependent patients, but which is best in which circumstances and for which treatment goals? To find out this review compared the medications’ performance when separately benchmarked against a placebo, bringing to bear much more data than is available from the few trials which directly compared the two drugs.

Key points From summary and commentary
• The medications naltrexone and acamprosate both modestly curtail drinking among alcohol-dependent patients, but it is unclear which is best in which circumstances and for which treatment goals.
• Rather than confining itself to direct comparisons of the drugs, the featured analysis addressed these issues by comparing the two medications’ performance when separately benchmarked against a placebo.
• Findings suggested naltrexone is best for patients who want to control their heavy drinking, acamprosate for those seeking abstinence. Both seem more effective when patients have detoxified and/or stopped drinking in the run-up to treatment.


Item Type
Article
Publication Type
International, Open Access, Review, Article
Drug Type
Alcohol
Intervention Type
Drug therapy, Treatment method
Date
December 2016
Pages
3 p.
Publisher
Drug and Alcohol Findings
Corporate Creators
Drug and Alcohol Findings
Place of Publication
London
Number
13 December 2016
EndNote

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