Home > The SCottish Alcoholic Liver disease Evaluation: A population-level matched cohort study of hospital-based costs, 1991-2011.

Bouttell, Janet and Lewsey, James and Geue, Claudia and Antony, Grace and Briggs, Andrew and McCartney, Gerry and Hutchinson, Sharon and Graham, Lesley and Heydtmann, Mathis [PLOS One] . (2016) The SCottish Alcoholic Liver disease Evaluation: A population-level matched cohort study of hospital-based costs, 1991-2011. Public Library of Science. PLoS ONE, 11 (10)

URL: http://journals.plos.org/plosone/article?id=10.137...

Studies assessing the costs of alcoholic liver disease are lacking. We aimed to calculate the costs of hospitalisations before and after diagnosis compared to population controls matched by age, sex and socio-economic deprivation. We aimed to use population level data to identify a cohort of individuals hospitalised for the first time with alcoholic liver disease in Scotland between 1991 and 2011.Incident cases were classified by disease severity, sex, age group, socio-economic deprivation and year of index admission. 5 matched controls for every incident case were identified from the Scottish population level primary care database.

Hospital costs were calculated for both cases and controls using length of stay from morbidity records and hospital-specific daily rates by specialty. Remaining lifetime costs were estimated using parametric survival models and predicted annual costs. 35,208 incident alcoholic liver disease hospitalisations were identified. Mean annual hospital costs for cases were 2.3 times that of controls pre diagnosis (£804 higher) and 10.2 times (£12,774 higher) post diagnosis. Mean incident admission cost was £6,663. Remaining lifetime cost for a male, 50-59 years old, living in the most deprived area diagnosed with acoholic liver disease was estimated to be £65,999 higher than the matched controls (£12,474 for 7.43 years remaining life compared to £1,224 for 21.8 years). In Scotland, alcoholic liver disease diagnosis is associated with significant increases in admissions to hospital both before and after diagnosis.

Our results provide robust population level estimates of costs of alcoholic liver disease for the purposes of health-care delivery, planning and future cost-effectiveness analyses.


Item Type:Evidence resource
Drug Type:Alcohol
Intervention Type:AOD disorder, AOD disorder harm reduction
Source:PLOS One
Date:October 2016
Page Range:e0162980
Publisher:Public Library of Science
Volume:11
Number:10
EndNote:View
Subjects:A Substance use, abuse, and dependence > Prevalence > Substance use behaviour > Alcohol consumption
B Substances > Alcohol
G Health and disease > State of health > Physical health
G Health and disease > Digestive system disorder > Liver disorder
J Health care, prevention and rehabilitation > Health care delivery
J Health care, prevention and rehabilitation > Health care programme or facility > Hospital
J Health care, prevention and rehabilitation > Health care economics
VA Geographic area > Europe > United Kingdom > Scotland

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