While prevalence levels of NPS use remain low in the general European population, there are important concerns with more problematic forms of use and harms. This short report provides an overview of the current situation in terms of NPS use and harms across Europe and reviews the available health- and drug-related interventions in that area.

Table of contents
• Executive summary
• Introduction
• School and family settings
• Nightlife settings
• Sexual health settings
• Emergency and clinical services
• Specialised treatment settings
• Low-threshold settings
• Prisons and custodial settings
• Internet and digital devices as platforms for the delivery of health responses and interventions
• Conclusion
• Consultation participants
• Project examples