Skip Page Header

Home > Antidepressants linked to suicide and aggression in teens.

Bazian. (2016) Antidepressants linked to suicide and aggression in teens. NHS Choices: Behind the headlines .

External website:

"Antidepressant use doubles the risk of suicide in under 18s and the risks to adults may have been seriously underestimated," The Daily Telegraph reports.


A review of clinical study reports compiled by drug companies also suggests that risks may have been under-reported. Clinical study reports usually have more detail than the summaries of published trial results. Researchers analysed 70 studies which looked at five antidepressants.They looked specifically at the reports of deaths, suicides, suicidal thinking or suicide attempts, aggression, and a type of extreme restlessness called akathisia.


The results showed that children taking antidepressants had a higher chance of suicidal thoughts or suicide attempts, and of aggression. None of the children in the studied died. Adults in the studies did not have an increased risk of these problems. The finding that children and young people are more likely to think about or attempt suicide while taking antidepressants is not new, and has been known for more than a decade.


The study authors criticised the small amount of data on harms available, and the way it was presented. They say this makes it difficult to calculate the true chance of harm from antidepressants. It is a potential concern that harms may have been under-reported by pharmaceutical companies. Only full disclosure of evidence can provide us with an accurate profile of both the risks and benefits of a treatment.


No-one should stop taking an antidepressant suddenly as a result of this study. If you are concerned about the risk of side effects, see your doctor. Stopping antidepressants suddenly can be dangerous…..

Repository Staff Only: item control page