Home > Antidepressants linked to suicide and aggression in teens.

Bazian. [NHS Choices] (2016) Antidepressants linked to suicide and aggression in teens. London: NHS Choices. NHS Choices: Behind the headlines

URL: http://www.nhs.uk/news/2016/01January/Pages/Antide...

"Antidepressant use doubles the risk of suicide in under 18s and the risks to adults may have been seriously underestimated," The Daily Telegraph reports.


A review of clinical study reports compiled by drug companies also suggests that risks may have been under-reported. Clinical study reports usually have more detail than the summaries of published trial results. Researchers analysed 70 studies which looked at five antidepressants.They looked specifically at the reports of deaths, suicides, suicidal thinking or suicide attempts, aggression, and a type of extreme restlessness called akathisia.


The results showed that children taking antidepressants had a higher chance of suicidal thoughts or suicide attempts, and of aggression. None of the children in the studied died. Adults in the studies did not have an increased risk of these problems. The finding that children and young people are more likely to think about or attempt suicide while taking antidepressants is not new, and has been known for more than a decade.


The study authors criticised the small amount of data on harms available, and the way it was presented. They say this makes it difficult to calculate the true chance of harm from antidepressants. It is a potential concern that harms may have been under-reported by pharmaceutical companies. Only full disclosure of evidence can provide us with an accurate profile of both the risks and benefits of a treatment.


No-one should stop taking an antidepressant suddenly as a result of this study. If you are concerned about the risk of side effects, see your doctor. Stopping antidepressants suddenly can be dangerous…..

Item Type:Evidence resource
Drug Type:CNS depressants
Intervention Type:AOD disorder, AOD disorder harm reduction
Source:NHS Choices
Date:28 January 2016
Publisher:NHS Choices
Corporate Creators:Bazian
Place of Publication:London
Subjects:A Substance use, abuse, and dependence > Effects and consequences
B Substances > Sedatives or tranquillisers (CNS depressants)
E Concepts in biomedical areas > Substance by legal status > Prescription drug (medicine / medication)
F Concepts in psychology > Specific attitude and behaviour > self-destructive behaviour > suicidal behaviour / suicide
J Health care, prevention and rehabilitation > Health related prevention > Health information and education > Suicide prevention
T Demographic characteristics > Adolescent / youth (teenager / young person)
VA Geographic area > Europe > United Kingdom

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