Home > Pharmacotherapies for cannabis use disorder.

Spiga, Francesca and Parkhouse, Thomas and Tang, Victor M and Savović, Jelena and Le Foll, Bernard and Nielsen, Suzanne (2025) Pharmacotherapies for cannabis use disorder. Cochrane Database of Systematic Reviews, (9), Art no. CD008940. DOI: 10.1002/14651858.CD008940.pub4.

External website: https://www.cochranelibrary.com/cdsr/doi/10.1002/1...


Conclusions: There is incomplete evidence for all the clinically‐important pharmacotherapies investigated and, for half of their outcomes, the quality of the evidence was low (44%) or very low (11%). Given the limited evidence of efficacy, those pharmacotherapies should still be considered experimental for treating cannabis use disorder. The greater withdrawal from treatment due to adverse effects seen with anticonvulsants and mood stabilisers may limit their therapeutic value. 

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