In this report, we set out a broad roadmap for getting drugs under control. We recognize that past approaches premised on a punitive law enforcement paradigm have failed, emphatically so. They have resulted in more violence, larger prison populations, and the erosion of governance around the world. The health harms associated with drug use have got worse, not better. The Global Commission on Drug Policy instead advocates for an approach to drug policy that puts public health, community safety, human rights, and development at the center.