Home > Health-related quality of life of HIV-infected intravenous drug users.

Surah, S and Adams, R and Townsend, L and Reynolds, I and Kinahan, J C and Keating, Shay and Mulcahy, Fiona and Keenan, Eamon and Barry, M and Lyons, F (2013) Health-related quality of life of HIV-infected intravenous drug users. International Journal of STD & AIDS, 24, (11), pp. 867-74. https://doi.org/10.1177/0956462413486454.

To investigate health-related quality of life in HIV-infected intravenous drug users registered but not engaged in HIV outpatient care (missing ≥2 outpatient appointments over 1 year or non-attendance for ≥6 months) we conducted a cross-sectional study to examine health-related quality of life of HIV-infected intravenous drug users registered for care at an inner city HIV unit. EQ-5D, SF-36, SF-6D, mood disorder, clinical and substance misuse data were collected. Mean scores and preference derived utility scores were calculated.

Statistical relationships between health-related quality of life and other variables were explored using univariate and multivariate analysis. Fifty-five patients were recruited, 64% were males. The mean anxiety value was 11.44 (anxious) and mean depression score was 9.3 (borderline depressed). The mean EQ-5D utility was 0.45 (95% CI 0.35, 0.55) and mean SF-6D utility was 0.52 (95% CI 0.48, 0.55). There was no statistical relationship between HIV indices, substance misuse and EQ-5D and SF-6D utility. Anxiety and depression were significantly correlated with EQ-5D and SF-6D utility values on univariate and multivariate analysis. Health-related quality of life was reduced in this HIV-infected intravenous drug user population. Whilst hepatitis C co-infection and substance misuse did not affect health-related quality of life, anxiety and depression had a significant impact on it.


Item Type
Article
Publication Type
Irish-related, Article
Drug Type
Substances (not alcohol/tobacco), Opioid
Intervention Type
Harm reduction
Date
2013
Identification #
https://doi.org/10.1177/0956462413486454
Page Range
pp. 867-74
Publisher
Royal Society of Medicine Press
Volume
24
Number
11
EndNote
Accession Number
HRB (Electronic Only)
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