Home > Anticonvulsants for alcohol dependence.

Pani, Pier Paolo and Trogu, Emanuela and Pacini, Matteo and Maremmani, Icro [The Cochrane Library] . (2014) Anticonvulsants for alcohol dependence. London: John Wiley & Sons, Ltd. Cochrane Database of Systematic Reviews (2) Art. No.: CD008544. DOI: 10.1002/14651858.CD008544.pub2

URL: http://onlinelibrary.wiley.com/doi/10.1002/1465185...

Background:
Alcohol dependence is a major public health problem characterised by recidivism and a host of medical and psychosocial complications. Together with psychosocial interventions, different pharmacological interventions have been tested in trials and systematic reviews. In this review, we wanted to discover whether anticonvulsants are better than placebo or are better than other medications, psychosocial interventions or no intervention.

Authors' conclusions:
At the current stage of research, evidence supporting the clinical use of anticonvulsants to treat alcohol dependence is insufficient. Results are conditioned by heterogeneity and by the low number and quality of studies comparing anticonvulsants versus other medications. The uncertainty associated with these results leaves to clinicians the need to balance the possible benefits/risks of treatment with anticonvulsants versus other medications as supported by evidence of efficacy.

 

Item Type:Evidence resource
Publication Type:Review
Drug Type:Alcohol
Intervention Type:AOD disorder drug therapy
Source:The Cochrane Library
Date:2014
Publisher:John Wiley & Sons, Ltd
Place of Publication:London
Number:2
EndNote:View
Accession Number:HRB (Not in collection)
Subjects:G Health and disease > Substance use disorder > Alcohol use > Alcohol dependence
B Substances > Alcohol
HJ Treatment method > Substance disorder treatment method > Substance disorder drug therapy

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