Home > Central cord syndrome in Ireland: the effect of age on clinical outcome.

Lenehan, Brian and Street, John and O'Toole, Patrick and Siddiqui, Atar and Poynton, Ashley (2009) Central cord syndrome in Ireland: the effect of age on clinical outcome. European Spine Journal , 18 , (10) , pp. 1458-63.

Central cord syndrome is an incomplete spinal cord injury. Records of all patients with acute traumatic central cord syndrome admitted to the National Spinal Injuries Unit from 1999 to 2007 were compiled from a prospectively collected computerized spinal database. Data recorded included patient demographic profile, mechanism of injury, initial neurological deficit, treatment instituted, complications of treatment, and final neurological status.

A total of 50 patients with acute traumatic central cord syndrome were identified accounting for 6.2% of all admissions to the spinal injuries unit. There were 42 men and 8 women. The mean age was 56.1 years with a range of 41-88 years. We stratified patients according to age at injury to determine the effect of age on clinical outcome.

More than one-third of patients were intoxicated with alcohol at the time of the injury. Both upper and lower limb motor scores and total sensory scores improved in all age groups. Absolute and relative improvements were greatest in patients <50 years of age. Sphincter disturbance was documented in 42% of all the patients on admission. At follow up 12% of patients had residual disturbance. At final follow up none of the patients under 70 years of age had residual sphincter disturbance while 60% of those aged >70 years group had. Both of these results reached statistical significance.

In conclusion, central cord syndrome is a common cause of acute traumatic neurological deficit, with alcohol intoxication being a common confounder at the time of injury. The clinical outcomes are significantly worse in patients aged 70 years or older.

 

Item Type:Article
Date:15 August 2009
Page Range:pp. 1458-63
Publisher:Springer
Volume:18
Number:10
EndNote:View
Accession Number:HRB (Not in collection)
Subjects:A Substance use, abuse, and dependence > Prevalence > Substance use behaviour > Alcohol consumption
A Substance use, abuse, and dependence > Effects and consequences
B Substances > Alcohol
G Health and disease > State of health > Physical health
VA Geographic area > Europe > Ireland

Click here to request a copy of this literature (must be logged in)

Repository Staff Only: item control page