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Griffiths, Paul N and Seyler, Thomas and De Morais, Joanna M and Mounteney, Jane E and Sedefov, Roumen S (2023) Editorial. Opioid problems are changing in Europe with worrying signals that synthetic opioids may play a more significant role in the future. Addiction, Early online, https://doi.org/10.1111/add.16420.