by Jie-Xin Deng, Xi Liu, Jian-Feng Zang, Hong-En Huang, Yan Xi, Hong Zheng, Huan-Ling Yao, Dong-Ming Yu, Jin-Bo Deng
Abstract:
Aims: Our aim is to investigate the effects of prenatal alcohol exposure (PAE) on the development of retinal bipolar and horizontal cells. Methods: The alterations of the retinal bipolar and horizontal cells in P7, P14 and P30 mice were observed after PAE, with immunofluorescent labeling and DiI diolistic assay. Results: The retinal development of filial pups was affected by PAE in a dose-dependent and long-term manner. The number of bipolar cells of alcohol groups was significantly lower than that of the control, and the dendritic receptive field of horizontal cells was also significantly smaller than those of the control groups (P
Reference:
The Effects of Prenatal Alcohol Exposure on the Developmental Retina of Mice (Jie-Xin Deng, Xi Liu, Jian-Feng Zang, Hong-En Huang, Yan Xi, Hong Zheng, Huan-Ling Yao, Dong-Ming Yu, Jin-Bo Deng), In Alcohol and Alcoholism, volume 47, no. 4, 2012.AbstractAims: Our aim is to investigate the effects of prenatal alcohol exposure (PAE) on the development of retinal bipolar and horizontal cells. Methods: The alterations of the retinal bipolar and horizontal cells in P7, P14 and P30 mice were observed after PAE, with immunofluorescent labeling and DiI diolistic assay. Results: The retinal development of filial pups was affected by PAE in a dose-dependent and long-term manner. The number of bipolar cells of alcohol groups was significantly lower than that of the control, and the dendritic receptive field of horizontal cells was also significantly smaller than those of the control groups (P
Bibtex Entry:
@article{doi:10.1093/alcalc/ags025,
author = {Deng, Jie-Xin and Liu, Xi and Zang, Jian-Feng and Huang, Hong-En and Xi, Yan and Zheng, Hong and Yao, Huan-Ling and Yu, Dong-Ming and Deng, Jin-Bo},
title = {The Effects of Prenatal Alcohol Exposure on the Developmental Retina of Mice},
journal = {Alcohol and Alcoholism},
volume = {47},
number = {4},
pages = {380},
year = {2012},
doi = {10.1093/alcalc/ags025},
URL = {http://dx.doi.org/10.1093/alcalc/ags025},
eprint = {https://academic.oup.com/oup/backfile/content_public/journal/alcalc/47/4/10.1093/alcalc/ags025/2/ags025.pdf}
,abstract = {<strong>Aims</strong>: Our aim is to investigate the effects of prenatal alcohol exposure (PAE) on the development of retinal bipolar and horizontal cells. <strong>Methods</strong>: The alterations of the retinal bipolar and horizontal cells in P7, P14 and P30 mice were observed after PAE, with immunofluorescent labeling and DiI diolistic assay. <strong>Results</strong>: The retinal development of filial pups was affected by PAE in a dose-dependent and long-term manner. The number of bipolar cells of alcohol groups was significantly lower than that of the control, and the dendritic receptive field of horizontal cells was also significantly smaller than those of the control groups (P },issn = 1464-3502}