This report is a five-year review, based on data returned to the Drug Misuse Research Division of the Health Research Board by the participating drug treatment centres. The report presents the main findings and observes any trends that have emerged over the five years 1990-1994 in treated drug misuse in the greater Dublin area. Noted trends include a steady increase in the number of cases who were treated for drug misuse, and a decrease in the proportion of those injecting their primary drug in favour of smoking. The report provides socio-demographic information, information on problem drug use and risk taking behaviour.