Smoking is one of the largest causes of death and disease in the developed world, responsible for 96,000 deaths per year in the UK. If current trends continue, it is estimated that globally, a billion lives will be lost to smoking-related diseases by the end of the 21st century. This briefing summarises the facts and figures around smoking cessation and the use of e-cigarettes for behaviour change in adults followed by public policy recommendations to facilitate smoking cessation.