In early June 2012, the ACMD became aware of a suspected 6-APB (“Benzofury”)-related death at the Scottish RockNess Music Festival, although this turned out not to be related to 6-APB, ACMD was prompted to review this series of chemicals. 5- and 6-APB were first mentioned in user forums in 2010. This report reviews the evidence of misuse and harm in relation to the benzofuran-type substances. The evidence concerning these substances and closely related analogues (see ―related compounds‖ and Annex A) was considered by the ACMD at meetings of the Novel Psychoactive Substances Committee and by the full Council in 2012 and 2013. A Temporary Class Drug Order (TCDO) for these substances and some closely related analogues came into force on 10 June 2013.