This bulletin provides an analysis of data collected in the first drug prevalence survey of households in Ireland and Northern Ireland on the use of Sedatives, Tranquillisers or Anti-depressants. The survey sampled a representative number of people aged between 15 and 64 during late 2002 and early 2003. This bulletin contains data on lifetime (ever used), last year (recent use) and last month (current use). It also investigates age of first use, frequency of use, method of taking sedatives, tranquillisers or anti-depressants, how they were obtained and presents a profile of users in this study.