This bulletin presents key findings at a local level from the second drug prevalence survey of households in both Ireland and Northern Ireland. The survey sampled a representative number of people aged between 15 and 64 during late 2006 and early 2007. The survey was carried out by Ipsos MORI in Ireland and by the Central Survey Unit of the Northern Ireland Statistics and Research Agency in Northern Ireland according to standards set by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA).This bulletin presents results relating to drug prevalence on a lifetime, last year (recent) and last month (current) basis for illegal and other drugs including alcohol and tobacco for each Regional Drug Task Force Area (former Health Board areas) in Ireland, and Health and Social Service Board (HSSB) in Northern Ireland.